Lineage for Superfamily a.118.8: TPR-like

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2338494Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2339718Superfamily a.118.8: TPR-like [48452] (10 families) (S)

Families:

  1. 2339719a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (21 proteins)
    this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain
  2. 2339900a.118.8.2: Transcription factor MalT domain III [69094] (1 protein)
  3. 2339904a.118.8.3: BTAD-like [140845] (1 protein)
    Pfam PF03704; Bacterial transcriptional activator domain
  4. 2339910a.118.8.4: PrgX C-terminal domain-like [140848] (2 proteins)
  5. 2339956a.118.8.5: Atu0120-like [158772] (1 protein)
    Pfam PF06041; DUF924
  6. 2339961a.118.8.6: SusD-like [158775] (4 proteins)
    TPR-like structure resides in the N-terminal part; the C-terminal part is structurally unique and is covered by Pfam PF07980
  7. 2339986a.118.8.7: HAT/Suf repeat [158782] (4 proteins)
    includes Pfam PF05843
    Pfam PF02184

    this is a repeat family; one repeat unit is 2ond A:372-408 found in domain
  8. 2340001a.118.8.8: CT2138-like [158785] (1 protein)
    probable biological unit is a homohexamer
    automatically mapped to Pfam PF12968

    this is a repeat family; one repeat unit is 2hr2 A:93-136 found in domain
  9. 2340010a.118.8.9: TPR-like repeats from PCI (proteasome / COP9 signalosome / eIF3) domains [345951] (10 proteins)
    N-terminal part of Pfam PF06272
    Described in PubMed 15180986 as 'HAM (HEAT analagous motif) domain'
    Probably homologous to TPR rather than HEAT, based on PubMed 15790418

    this is a repeat family; one repeat unit is 4cr2 O:123-163 found in domain
  10. 2340047a.118.8.0: automated matches [191581] (1 protein)
    not a true family

More info for Superfamily a.118.8: TPR-like

Timeline for Superfamily a.118.8: TPR-like: