SCOPe 2.06: Domain d2xdta2: 2xdt A:255-529

Lineage for d2xdta2 (2xdt A:255-529)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.13: Zn aminopeptidase catalytic domain [64338] (5 proteins)
   adopts thermolysin-like fold

6. Protein ERAP1 catalytic domain [254382] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254815] (2 PDB entries)

8. Domain d2xdta2: 2xdt A:255-529 [304635]
   Other proteins in same PDB: d2xdta1, d2xdta3, d2xdta4
   automated match to d2yd0a2
   complexed with edo, k, nag, zn

Details for d2xdta2

PDB Entry: 2xdt, 2.7 Å

PDB Description: crystal structure of the soluble domain of human endoplasmic reticulum aminopeptidase 1 erap1

PDB Compounds: (A:) endoplasmic reticulum aminopeptidase 1

SCOPe Domain Sequences for d2xdta2:

Sequence, based on SEQRES records:

>d2xdta2 d.92.1.13 (A:255-529) ERAP1 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
esvskitksgvkvsvyavpdkinqadyaldaavtllefyedyfsipyplpkqdlaaipdf
qsgamenwglttyresallfdaekssassklgitmtvahelahqwfgnlvtmewwndlwl
negfakfmefvsvsvthpelkvgdyffgkcfdamevdalnsshpvstpvenpaqiremfd
dvsydkgacilnmlreylsadafksgivqylqkhsykntknedlwdsmasicptdgvkgm
dgfcsrsqhssssshwhqegvdvktmmntwtlqkg

Sequence, based on observed residues (ATOM records):

>d2xdta2 d.92.1.13 (A:255-529) ERAP1 catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
esvskitksgvkvsvyavpdkinqadyaldaavtllefyedyfsipyplpkqdlaaipdf
qsgamenwglttyresallfdaekssassklgitmtvahelahqwfgnlvtmewwndlwl
negfakfmefvsvsvthpelkvgdyffgkcfdamevdalnsshpvstpvenpaqiremfd
dvsydkgacilnmlreylsadafksgivqylqkhsykntknedlwdsmasigvdvktmmn
twtlqkg

Timeline for d2xdta2:

• d2xdta2 is new in SCOPe 2.06-stable
  
• d2xdta2 appears in SCOPe 2.07
  
• d2xdta2 appears in the current release, SCOPe 2.08