SCOPe 2.08: Domain d2fnzb4: 2fnz B:165-333

Lineage for d2fnzb4 (2fnz B:165-333)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (20 species)

7. Species Cryptosporidium parvum [TaxId:5807] [225186] (10 PDB entries)

8. Domain d2fnzb4: 2fnz B:165-333 [303877]
   Other proteins in same PDB: d2fnza3, d2fnzb3
   automated match to d4nd1a2
   complexed with gol, nad, oxm, so4

Details for d2fnzb4

PDB Entry: 2fnz, 2.5 Å

PDB Description: Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid)

PDB Compounds: (B:) lactate dehydrogenase

SCOPe Domain Sequences for d2fnzb4:

Sequence; same for both SEQRES and ATOM records:

>d2fnzb4 d.162.1.1 (B:165-333) Lactate dehydrogenase {Cryptosporidium parvum [TaxId: 5807]}
gvldssrfrtfiaqhfgvnasdvsanvigghgdgmvpatssvsvggvplssfikqglitq
eqideivchtriawkevadnlktgtayfapaaaavkmaeaylkdkkavvpcsafcsnhyg
vkgiymgvptiigkngvedileldltpleqkllgesinevntiskvldnap

Timeline for d2fnzb4:

• d2fnzb4 first appeared in SCOPe 2.06
  
• d2fnzb4 appears in SCOPe 2.07