SCOPe 2.07: Domain d1qmma2: 1qmm A:357-522

Lineage for d1qmma2 (1qmm A:357-522)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
   two constituent families are related by circular permutation

5. Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)

6. Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [49571] (6 PDB entries)

8. Domain d1qmma2: 1qmm A:357-522 [302956]
   Other proteins in same PDB: d1qmma1, d1qmma3, d1qmma4, d1qmma5
   automated match to d1e8xa2
   complexed with atp, lu

Details for d1qmma2

PDB Entry: 1qmm, 2.2 Å

PDB Description: structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling

PDB Compounds: (A:) phosphatidylinositol 3-kinase catalytic subunit

SCOPe Domain Sequences for d1qmma2:

Sequence, based on SEQRES records:

>d1qmma2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa) [TaxId: 9823]}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycgkapalsgktsaempspeskgkaqllyyvnlllidhrfllr
hgeyvlhmwqlsgkgedqgsfnadkltsatnpdkensmsisilldn

Sequence, based on observed residues (ATOM records):

>d1qmma2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa) [TaxId: 9823]}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycqllyyvnlllidhrfllrhgeyvlhmwqlsgfnadkltsat
npdkensmsisilldn

Timeline for d1qmma2:

• d1qmma2 first appeared in SCOPe 2.06
  
• d1qmma2 appears in the current release, SCOPe 2.08