SCOP 1.63: Domain d1ahia_: 1ahi A:

Lineage for d1ahia_ (1ahi A:)

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (31 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein 7-alpha-hydroxysteroid dehydrogenase [51774] (1 species)

7. Species Escherichia coli [TaxId:562] [51775] (3 PDB entries)

8. Domain d1ahia_: 1ahi A: [29858]

Details for d1ahia_

PDB Entry: 1ahi, 2.3 Å

PDB Description: 7 alpha-hydroxysteroid dehydrogenase complexed with nadh and 7-oxo glycochenodeoxycholic acid

SCOP Domain Sequences for d1ahia_:

Sequence; same for both SEQRES and ATOM records:

>d1ahia_ c.2.1.2 (A:) 7-alpha-hydroxysteroid dehydrogenase {Escherichia coli}
mfnsdnlrldgkcaiitgagagigkeiaitfatagasvvvsdinadaanhvvdeiqqlgg
qafacrcditseqelsaladfaisklgkvdilvnnaggggpkpfdmpmadfrrayelnvf
sffhlsqlvapemekngggviltitsmaaenkninmtsyasskaaashlvrnmafdlgek
nirvngiapgailtdalksvitpeieqkmlqhtpirrlgqpqdianaalflcspaaswvs
gqiltvsgggvqeln

Timeline for d1ahia_:

• d1ahia_ first appeared (with stable ids) in SCOP 1.55
  
• d1ahia_ appears in SCOP 1.61
  
• d1ahia_ appears in SCOP 1.65
  
• d1ahia_ appears in the current release, SCOPe 2.08