SCOPe 2.01: Domain d2isda3: 2isd A:299-625

Lineage for d2isda3 (2isd A:299-625)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.18: PLC-like phosphodiesterases [51695] (4 families)

5. Family c.1.18.1: Mammalian PLC [51696] (2 proteins)

6. Protein Phospholipase C isozyme D1 (PLC-D1) [51697] (1 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [51698] (10 PDB entries)

8. Domain d2isda3: 2isd A:299-625 [29597]
   Other proteins in same PDB: d2isda1, d2isda2, d2isdb1, d2isdb2
   complexed with act

Details for d2isda3

PDB Entry: 2isd, 2.5 Å

PDB Description: phosphoinositide-specific phospholipase c-delta1 from rat

PDB Compounds: (A:) phosphoinositide-specific phospholipase c, isozyme delta1

SCOPe Domain Sequences for d2isda3:

Sequence, based on SEQRES records:

>d2isda3 c.1.18.1 (A:299-625) Phospholipase C isozyme D1 (PLC-D1) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dqplshylvssshntylledqltgpssteayiralckgcrcleldcwdgpnqepiiyhgy
tftskilfcdvlrairdyafkaspypvilslenhcsleqqrvmarhlrailgpilldqpl
dgvttslpspeqlkgkillkgkklggllpaggengseatdvsdeveaaemedeavrsqvq
hkpkedklklvpelsdmiiycksvhfggfsspgtsgqafyemasfsesralrllqesgng
fvrhnvsclsriypagwrtdssnyspvemwnggcqivalnfqtpgpemdvylgcfqdngg
cgyvlkpaflrdpnttfnsraltqgpw

Sequence, based on observed residues (ATOM records):

>d2isda3 c.1.18.1 (A:299-625) Phospholipase C isozyme D1 (PLC-D1) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dqplshylvssshntylledqltgpssteayiralckgcrcleldcwdgpnqepiiyhgy
tftskilfcdvlrairdyafkaspypvilslenhcsleqqrvmarhlrailgpilldqpl
dgvttslpspeqlkgkillkgkklklvpelsdmiiycksvhfggfsspgtsgqafyemas
fsesralrllqesgngfvrhnvsclsriypagwrtdssnyspvemwnggcqivalnfqtp
gpemdvylgcfqdnggcgyvlkpaflrdpnttfnsraltqgpw

Timeline for d2isda3:

• d2isda3 first appeared (with stable ids) in SCOP 1.55
  
• d2isda3 appears in SCOP 1.75
  
• d2isda3 appears in SCOPe 2.02
  
• d2isda3 appears in the current release, SCOPe 2.08