SCOP 1.71: Domain d1ald__: 1ald -

Lineage for d1ald__ (1ald -)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (6 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (12 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Fructose-1,6-bisphosphate aldolase [51576] (8 species)

7. Species Human (Homo sapiens), muscle isozyme [TaxId:9606] [51577] (3 PDB entries)

8. Domain d1ald__: 1ald - [29100]

Details for d1ald__

PDB Entry: 1ald, 2 Å

PDB Description: activity and specificity of human aldolases

SCOP Domain Sequences for d1ald__:

Sequence; same for both SEQRES and ATOM records:

>d1ald__ c.1.10.1 (-) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), muscle isozyme}
pyqypaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrq
llltaddrvnpciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtng
etttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqn
givpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghact
qkfsheeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfs
ygralqasalkawggkkenlkaaqeeyvkralanslacqgkytpsgqagaaaseslfvsn
hay

Timeline for d1ald__:

• d1ald__ first appeared (with stable ids) in SCOP 1.55
  
• d1ald__ appears in SCOP 1.69
  
• d1ald__ is called d1alda_ in SCOP 1.73
  
• d1ald__ appears in the current release, SCOPe 2.08, called d1alda_