SCOP 1.71: Domain d1f7bc_: 1f7b C:

Lineage for d1f7bc_ (1f7b C:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (6 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (12 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein N-acetylneuraminate lyase [51571] (2 species)

7. Species Haemophilus influenzae [TaxId:727] [51573] (6 PDB entries)

8. Domain d1f7bc_: 1f7b C: [29084]
   complexed with cl, nau, nav

Details for d1f7bc_

PDB Entry: 1f7b, 1.8 Å

PDB Description: crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii in complex with 4-oxo-sialic acid

SCOP Domain Sequences for d1f7bc_:

Sequence, based on SEQRES records:

>d1f7bc_ c.1.10.1 (C:) N-acetylneuraminate lyase {Haemophilus influenzae}
mrdlkgifsallvsfnedgtinekglrqiirhnidkmkvdglyvggstgenfmlsteekk
eifriakdeakdqialiaqvgsvnlkeavelgkyatelgydclsavtpfyykfsfpeikh
yydtiiaetgsnmivysipfltgvnmgieqfgelyknpkvlgvkftagdfyllerlkkay
pnhliwagfdemmlpaaslgvdgaigstfnvngvrarqifeltkagklkealeiqhvtnd
liegilanglyltikellklegvdagycrepmtskataeqvakakdlkakfls

Sequence, based on observed residues (ATOM records):

>d1f7bc_ c.1.10.1 (C:) N-acetylneuraminate lyase {Haemophilus influenzae}
mrdlkgifsallvsfnedgtinekglrqiirhnidkmkvdglyvggstgenfmlsteekk
eifriakdeakdqialiaqvgsvnlkeavelgkyatelgydclsavtpfyykfsfpeikh
yydtiiaetgsnmivysmgieqfgelyknpkvlgvkftagdfyllerlkkaypnhliwag
fdemmlpaaslgvdgaigstfnvngvrarqifeltkagklkealeiqhvtndliegilan
glyltikellklegvdagycrepmtskataeqvakakdlkakfls

Timeline for d1f7bc_:

• d1f7bc_ first appeared (with stable ids) in SCOP 1.55
  
• d1f7bc_ appears in SCOP 1.69
  
• d1f7bc_ appears in SCOP 1.73
  
• d1f7bc_ appears in the current release, SCOPe 2.08