SCOPe 2.06: Domain d2n1tc_: 2n1t C:

Lineage for d2n1tc_ (2n1t C:)

1. Root: SCOPe 2.06

2. Class h: Coiled coil proteins [57942] (7 folds)

3. Fold h.1: Parallel coiled-coil [57943] (38 superfamilies)
   this is not a true fold; includes oligomers of shorter identical helices

4. Superfamily h.1.15: SNARE fusion complex [58038] (2 families)
   tetrameric parallel coiled coil

5. Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)

6. Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
   provides up to two different helical regions to synaptic fusion complexes

7. Species Human (Homo sapiens) [TaxId:9606] [88917] (5 PDB entries)
   Uniprot P60880 146-204 # identical sequence to rat species

8. Domain d2n1tc_: 2n1t C: [273433]
   Other proteins in same PDB: d2n1ta_, d2n1tb_, d2n1te1, d2n1te2
   automated match to d1n7sc_

Details for d2n1tc_

PDB Entry: 2n1t

PDB Description: dynamic binding mode of a synaptotagmin-1-snare complex in solution

PDB Compounds: (C:) synaptosomal-associated protein 25

SCOPe Domain Sequences for d2n1tc_:

Sequence; same for both SEQRES and ATOM records:

>d2n1tc_ h.1.15.1 (C:) Synaptosomal-associated protein SNAP-25 {Human (Homo sapiens) [TaxId: 9606]}
mrneleemqrradqladeslestrrmlqlveeskdagirtlvmldeqgeqldrveegmnh
inqdmkeaeknlkdlgk

Timeline for d2n1tc_:

• d2n1tc_ first appeared in SCOPe 2.05
  
• d2n1tc_ appears in SCOPe 2.07
  
• d2n1tc_ appears in the current release, SCOPe 2.08