SCOPe 2.06: Domain d4rn0b1: 4rn0 B:14-377

Lineage for d4rn0b1 (4rn0 B:14-377)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (33 PDB entries)

8. Domain d4rn0b1: 4rn0 B:14-377 [271227]
   Other proteins in same PDB: d4rn0a2, d4rn0b2
   automated match to d4qa0a_
   complexed with gol, imd, k, l6g, zn

Details for d4rn0b1

PDB Entry: 4rn0, 1.76 Å

PDB Description: crystal structure of s39d hdac8 in complex with a largazole analogue.

PDB Compounds: (B:) Histone deacetylase 8

SCOPe Domain Sequences for d4rn0b1:

Sequence, based on SEQRES records:

>d4rn0b1 c.42.1.2 (B:14-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khvv

Sequence, based on observed residues (ATOM records):

>d4rn0b1 c.42.1.2 (B:14-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqhpdsieygldcpategifdyaaaiggatitaaqclidgmckvainwsgg
whhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvsl
hkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkav
vlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltg
vilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv

Timeline for d4rn0b1:

• d4rn0b1 first appeared in SCOPe 2.05, called d4rn0b_
  
• d4rn0b1 appears in SCOPe 2.07
  
• d4rn0b1 appears in the current release, SCOPe 2.08