SCOPe 2.07: Domain d4rzeb_: 4rze B:

Lineage for d4rzeb_ (4rze B:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Orphan nuclear receptor NR4A1 [158811] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158812] (15 PDB entries)
   Uniprot P22736 363-595

8. Domain d4rzeb_: 4rze B: [270438]
   automated match to d3v3qa1
   complexed with gol; mutant

Details for d4rzeb_

PDB Entry: 4rze, 2.49 Å

PDB Description: crystal structure analysis of the nur77 ligand binding domain, l437w, d594e mutant

PDB Compounds: (B:) Nuclear receptor subfamily 4 group A member 1

SCOPe Domain Sequences for d4rzeb_:

Sequence, based on SEQRES records:

>d4rzeb_ a.123.1.1 (B:) Orphan nuclear receptor NR4A1 {Human (Homo sapiens) [TaxId: 9606]}
anlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkwa
ekipgfaelspadqdwllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgd
widsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaa
vagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiidkifmetlpf

Sequence, based on observed residues (ATOM records):

>d4rzeb_ a.123.1.1 (B:) Orphan nuclear receptor NR4A1 {Human (Homo sapiens) [TaxId: 9606]}
anlltslvrahldsgpstakldyskfqelvlkedagdvqqfydllsgslevirkwaekip
gfaelspadqdwllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgdwids
ilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaavaga
sclsrllgklpelrtlctqglqrifylkledlvppppiidkifmetlpf

Timeline for d4rzeb_:

• d4rzeb_ first appeared in SCOPe 2.05
  
• d4rzeb_ appears in SCOPe 2.06
  
• d4rzeb_ appears in the current release, SCOPe 2.08