PDB entry 4rze

View 4rze on RCSB PDB site
Description: Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
Class: transcription
Keywords: transcription
Deposited on 2014-12-21, released 2015-03-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRP1, HMR, NAK1, NR4A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-247)
      • engineered mutation (86)
      • engineered mutation (243)
    Domains in SCOPe 2.07: d4rzea_
  • Chain 'B':
    Compound: Nuclear receptor subfamily 4 group A member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRP1, HMR, NAK1, NR4A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22736 (Start-247)
      • engineered mutation (86)
      • engineered mutation (243)
    Domains in SCOPe 2.07: d4rzeb_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4rzeA (A:)
skpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydll
sgslevirkwaekipgfaelspadqdwllesaflelfilrlayrskpgegklifcsglvl
hrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnr
iasclkehvaavagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiidk
ifmetlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4rzeA (A:)
anlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydllsgslevirkwa
ekipgfaelspadqdwllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgd
widsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaa
vaasclsrllgklpelrtlctqglqrifylkledlvppppiidkifmetlpf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4rzeB (B:)
skpkqppdaspanlltslvrahldsgpstakldyskfqelvlphfgkedagdvqqfydll
sgslevirkwaekipgfaelspadqdwllesaflelfilrlayrskpgegklifcsglvl
hrlqcargfgdwidsilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnr
iasclkehvaavagepqpasclsrllgklpelrtlctqglqrifylkledlvppppiidk
ifmetlpflehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4rzeB (B:)
anlltslvrahldsgpstakldyskfqelvlkedagdvqqfydllsgslevirkwaekip
gfaelspadqdwllesaflelfilrlayrskpgegklifcsglvlhrlqcargfgdwids
ilafsrslhsllvdvpafaclsalvlitdrhglqeprrveelqnriasclkehvaavaga
sclsrllgklpelrtlctqglqrifylkledlvppppiidkifmetlpf