SCOP 1.59: Domain d2thf.1: 2thf A:,B:

Lineage for d2thf.1 (2thf A:,B:)

1. Root: SCOP 1.59

2. Class b: All beta proteins [48724] (110 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (36 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (126 PDB entries)

8. Domain d2thf.1: 2thf A:,B: [26139]

Details for d2thf.1

PDB Entry: 2thf, 2.1 Å

PDB Description: structure of human alpha-thrombin y225f mutant bound to d-phe-pro-arg-chloromethylketone

SCOP Domain Sequences for d2thf.1:

Sequence, based on SEQRES records:

>g2thf.1 b.47.1.2 (A:,B:) Thrombin {Human (Homo sapiens)}
dcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanvg
kgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmks
pfnnrwyqmgivswgegcdrdgkfgfythvfrlkkwiqkvidqf

Sequence, based on observed residues (ATOM records):

>g2thf.1 b.47.1.2 (A:,B:) Thrombin {Human (Homo sapiens)}
dcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqpsvlq
vvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyq
mgivswgegcdrdgkfgfythvfrlkkwiqkvidqf

Timeline for d2thf.1:

• d2thf.1 first appeared (with stable ids) in SCOP 1.55
  
• d2thf.1 appears in SCOP 1.57
  
• d2thf.1 appears in SCOP 1.61
  
• d2thf.1 appears in the current release, SCOPe 2.08