SCOPe 2.07: Domain d4bmma1: 4bmm A:32-477

Lineage for d4bmma1 (4bmm A:32-477)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (95 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:353153] [256563] (1 PDB entry)

8. Domain d4bmma1: 4bmm A:32-477 [256564]
   Other proteins in same PDB: d4bmma2, d4bmmb2, d4bmmc2, d4bmmd2
   automated match to d3khma_
   complexed with hem, tu1

Details for d4bmma1

PDB Entry: 4bmm, 2.84 Å

PDB Description: Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-2',3, 5'-trifluoro-(1,1'-biphenyl)-4-carboxamide

PDB Compounds: (A:) Sterol 14-alpha demethylase

SCOPe Domain Sequences for d4bmma1:

Sequence, based on SEQRES records:

>d4bmma1 a.104.1.0 (A:32-477) automated matches {Trypanosoma cruzi [TaxId: 353153]}
ppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrffs
prneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhevr
kfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmesslipa
avfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllkavyr
dgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqln
ydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhde
eafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrde
vpdpdyhtmvvgptlnqclvkytrkk

Sequence, based on observed residues (ATOM records):

>d4bmma1 a.104.1.0 (A:32-477) automated matches {Trypanosoma cruzi [TaxId: 353153]}
ppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrffs
prneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhevr
kfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmesslipa
avfmpwllrlplpqsarcrearaelqkilgeiivarekeesdllggllkavyrdgtrmsl
hevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnydnvmde
mpfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeeafpnpr
lwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevpdpdyh
tmvvgptlnqclvkytrkk

Timeline for d4bmma1:

• d4bmma1 first appeared in SCOPe 2.04, called d4bmma_
  
• d4bmma1 appears in SCOPe 2.06
  
• d4bmma1 appears in the current release, SCOPe 2.08