SCOPe 2.04: Domain d4emta_: 4emt A:

Lineage for d4emta_ (4emt A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.387: STING C-terminal-like [254119] (1 superfamily)
   5 helices and 5 strands in one mixed beta-sheet, one long bent helix

4. Superfamily d.387.1: STING, TM173 CTD-like [254144] (1 family)
   Pfam PF15009, PubMed 22579474

5. Family d.387.1.1: Tyrosinase cofactor MelC1 [254191] (2 proteins)

6. Protein Tyrosinase cofactor MelC1 [254420] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254863] (17 PDB entries)

8. Domain d4emta_: 4emt A: [251779]
   automated match to d4ef5a_
   complexed with c2e, ca

Details for d4emta_

PDB Entry: 4emt, 1.5 Å

PDB Description: Crystal Structure of human STING bound to c-di-GMP

PDB Compounds: (A:) Transmembrane protein 173

SCOPe Domain Sequences for d4emta_:

Sequence, based on SEQRES records:

>d4emta_ d.387.1.1 (A:) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsq
ysqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhl
rqee

Sequence, based on observed residues (ATOM records):

>d4emta_ d.387.1.1 (A:) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
svahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnls
madpnirfldklpqdrvysnsiyellengqragtcvleyatplqtlfamsqysqagfsre
drleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhlrqee

Timeline for d4emta_:

• d4emta_ is new in SCOPe 2.04-stable
  
• d4emta_ appears in SCOPe 2.05
  
• d4emta_ appears in the current release, SCOPe 2.08, called d4emta1