SCOPe 2.08: Domain d4emta1: 4emt A:155-337

Lineage for d4emta1 (4emt A:155-337)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.387: STING C-terminal-like [254119] (1 superfamily)
   5 helices and 5 strands in one mixed beta-sheet, one long bent helix

4. Superfamily d.387.1: STING, TM173 CTD-like [254144] (2 families)
   Pfam PF15009, PubMed 22579474

5. Family d.387.1.1: Tyrosinase cofactor MelC1 [254191] (2 proteins)

6. Protein Tyrosinase cofactor MelC1 [254420] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254863] (48 PDB entries)

8. Domain d4emta1: 4emt A:155-337 [251779]
   Other proteins in same PDB: d4emta2, d4emtb2
   automated match to d4ef5a_
   complexed with c2e, ca

Details for d4emta1

PDB Entry: 4emt, 1.5 Å

PDB Description: Crystal Structure of human STING bound to c-di-GMP

PDB Compounds: (A:) Transmembrane protein 173

SCOPe Domain Sequences for d4emta1:

Sequence, based on SEQRES records:

>d4emta1 d.387.1.1 (A:155-337) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
vahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnlsm
adpnirfldklpqqtgdhagikdrvysnsiyellengqragtcvleyatplqtlfamsqy
sqagfsredrleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhlr
qee

Sequence, based on observed residues (ATOM records):

>d4emta1 d.387.1.1 (A:155-337) Tyrosinase cofactor MelC1 {Human (Homo sapiens) [TaxId: 9606]}
vahglawsyyigylrlilpelqarirtynqhynnllrgavsqrlyillpldcgvpdnlsm
adpnirfldklpqdrvysnsiyellengqragtcvleyatplqtlfamsqysqagfsred
rleqaklfcrtlediladapesqnncrliayqepaddssfslsqevlrhlrqee

Timeline for d4emta1:

• d4emta1 first appeared in SCOPe 2.04, called d4emta_
  
• d4emta1 appears in SCOPe 2.07