SCOPe 2.07: Domain d3mgha3: 3mgh A:386-575

Lineage for d3mgha3 (3mgh A:386-575)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase lambda [102943] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102944] (27 PDB entries)

8. Domain d3mgha3: 3mgh A:386-575 [247696]
   Other proteins in same PDB: d3mgha1, d3mgha2, d3mghc1, d3mghc2
   automated match to d1rzta3
   protein/DNA complex; complexed with na; mutant

Details for d3mgha3

PDB Entry: 3mgh, 2.4 Å

PDB Description: binary complex of a dna polymerase lambda loop mutant

PDB Compounds: (A:) DNA polymerase lambda

SCOPe Domain Sequences for d3mgha3:

Sequence, based on SEQRES records:

>d3mgha3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvkgetkylgvcrlpgpgrrhrrldiivvpysefacallyftgsa
hfnrsmralaktkgmslsehalstavvrnthgckvgpgrvlptptekdvfrllglpyrep
aerdw

Sequence, based on observed residues (ATOM records):

>d3mgha3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvkgetkylgvcrlpgpgrrhrrldiivvpysefacallyftgsa
hfnrsmralaktkgmslsehalstavvrnckvgpgrvlptptekdvfrllglpyrepaer
dw

Timeline for d3mgha3:

• d3mgha3 first appeared in SCOPe 2.04
  
• d3mgha3 appears in SCOPe 2.06
  
• d3mgha3 appears in the current release, SCOPe 2.08