Lineage for d2wwja_ (2wwj A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2403751Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2404605Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2404954Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
  6. 2404958Protein JMJD2A core [254342] (1 species)
  7. 2404959Species Human (Homo sapiens) [TaxId:9606] [254775] (43 PDB entries)
  8. 2404974Domain d2wwja_: 2wwj A: [244349]
    automated match to d4bisa_
    complexed with ni, y28, zn

Details for d2wwja_

PDB Entry: 2wwj (more details), 2.6 Å

PDB Description: structure of jmjd2a complexed with inhibitor 10a
PDB Compounds: (A:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d2wwja_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2wwja_ b.82.2.14 (A:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
lnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvi
papiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltf
nppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfaw
htedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlisp
lmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcs
crkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef

SCOPe Domain Coordinates for d2wwja_:

Click to download the PDB-style file with coordinates for d2wwja_.
(The format of our PDB-style files is described here.)

Timeline for d2wwja_: