Lineage for Family b.82.2.14: Jumonji domain / Histone demethylase core

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
    Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811)

Proteins:

  1. JHDM2B core [254344] (1 species)
  2. JMJD2A core [254342] (1 species)
  3. JMJD2D core [254343] (1 species)
  4. automated matches [254635] (1 species)
    not a true protein
  5. KDM5B (JARID1B or PLU1) core [419085] (1 species)
  6. JHDM1A core [419130] (1 species)
  7. PHD finger protein 8 (PHF8) [419131] (1 species)

More info for Family b.82.2.14: Jumonji domain / Histone demethylase core

Timeline for Family b.82.2.14: Jumonji domain / Histone demethylase core: