Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2070014Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2070786Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2071116Family b.82.2.14: Histone demethylase core [254153] (4 protein domains)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
  6. 2071120Protein JMJD2A core [254342] (1 species)
  7. 2071121Species Human (Homo sapiens) [TaxId:9606] [254775] (41 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2gp3:
    1. 2071159Domain d2gp3a_: 2gp3 A: [241943]
      automated match to d2gp5a_
      complexed with fe2, zn
    2. 2071160Domain d2gp3b_: 2gp3 B: [241944]
      automated match to d2gp5a_
      complexed with fe2, zn
  2. Domain(s) for 2gp5:
    1. 2071152Domain d2gp5a_: 2gp5 A: [241945]
      complexed with akg, fe2, zn
    2. 2071153Domain d2gp5b_: 2gp5 B: [241946]
      complexed with akg, fe2, zn
  3. Domain(s) for 2oq7:
    1. 2071124Domain d2oq7a_: 2oq7 A: [243356]
      automated match to d4bisa_
      complexed with ni, oga, zn
    2. 2071125Domain d2oq7b_: 2oq7 B: [243357]
      automated match to d4bisa_
      complexed with ni, oga, zn
  4. Domain(s) for 2p5b:
    1. 2071138Domain d2p5ba_: 2p5b A: [243411]
      automated match to d2gp5a_
      complexed with fe2, oga, oxy, zn
    2. 2071139Domain d2p5bb_: 2p5b B: [243412]
      automated match to d2gp5a_
      complexed with fe2, oga, oxy, zn
  5. Domain(s) for 2vd7:
    1. 2071136Domain d2vd7a_: 2vd7 A: [243859]
      automated match to d4bisa_
      complexed with ni, pd2, zn
    2. 2071137Domain d2vd7b_: 2vd7 B: [243860]
      automated match to d4bisa_
      complexed with ni, pd2, zn
  6. Domain(s) for 2wwj:
    1. 2071140Domain d2wwja_: 2wwj A: [244349]
      automated match to d4bisa_
      complexed with ni, y28, zn
    2. 2071141Domain d2wwjb_: 2wwj B: [244350]
      automated match to d4bisa_
      complexed with ni, y28, zn
  7. Domain(s) for 2ybk:
    1. 2071134Domain d2ybka_: 2ybk A: [244720]
      automated match to d4bisa_
      complexed with 2hg, cl, ni, zn
    2. 2071135Domain d2ybkb_: 2ybk B: [244721]
      automated match to d4bisa_
      complexed with 2hg, cl, ni, zn
  8. Domain(s) for 3njy:
    1. 2071132Domain d3njya_: 3njy A: [247954]
      automated match to d4bisa_
      complexed with 8xq, ni, zn
    2. 2071133Domain d3njyb_: 3njy B: [247955]
      automated match to d4bisa_
      complexed with 8xq, ni, zn
  9. Domain(s) for 3pdq:
    1. 2071128Domain d3pdqa_: 3pdq A: [248469]
      automated match to d4bisa_
      complexed with cl, kc6, na, ni, zn
    2. 2071129Domain d3pdqb_: 3pdq B: [248470]
      automated match to d4bisa_
      complexed with cl, kc6, na, ni, zn
  10. Domain(s) for 3rvh:
    1. 2071126Domain d3rvha_: 3rvh A: [249236]
      automated match to d4bisa_
      complexed with gol, hq2, ni, zn
    2. 2071127Domain d3rvhb_: 3rvh B: [249237]
      automated match to d4bisa_
      complexed with gol, hq2, ni, zn
  11. Domain(s) for 4ai9:
    1. 2071130Domain d4ai9a_: 4ai9 A: [251039]
      automated match to d4bisa_
      complexed with cl, dza, gol, ni, zn
    2. 2071131Domain d4ai9b_: 4ai9 B: [251040]
      automated match to d4bisa_
      complexed with cl, dza, gol, ni, zn
  12. Domain(s) for 4bis:
    1. 2071148Domain d4bisa_: 4bis A: [251263]
      complexed with 8hq, cl, gol, ni, zn
    2. 2071149Domain d4bisb_: 4bis B: [251264]
      complexed with 8hq, cl, gol, ni, zn
  13. Domain(s) for 4gd4:
    1. 2071144Domain d4gd4a_: 4gd4 A: [252204]
      automated match to d4bisa_
      complexed with 0ws, cl, ni, zn
    2. 2071145Domain d4gd4b_: 4gd4 B: [252205]
      automated match to d4bisa_
      complexed with 0ws, cl, ni, zn
  14. Domain(s) for 4ura:
    1. 2071150Domain d4uraa_: 4ura A: [273927]
      automated match to d4v2wb_
      complexed with edo, lel, ni, so4, zn
    2. 2071151Domain d4urab_: 4ura B: [273928]
      automated match to d4v2wb_
      complexed with edo, lel, ni, so4, zn
  15. Domain(s) for 4v2w:
    1. 2071122Domain d4v2wa_: 4v2w A: [261305]
      automated match to d4bisa_
      complexed with cl, gol, ni, oga, zn
    2. 2071123Domain d4v2wb_: 4v2w B: [261304]
      automated match to d4bisa_
      complexed with cl, gol, ni, oga, zn
  16. Domain(s) for 5a7n:
    1. 2071161Domain d5a7na_: 5a7n A: [280228]
      automated match to d4bisa_
      complexed with edo, mn, so4, vao, zn
    2. 2071162Domain d5a7nb_: 5a7n B: [280229]
      automated match to d4bisa_
      complexed with edo, mn, so4, vao, zn
  17. Domain(s) for 5a7p:
    1. 2071154Domain d5a7pa_: 5a7p A: [280223]
      automated match to d4bisa_
      complexed with 6z1, dms, edo, mn, so4, zn
    2. 2071155Domain d5a7pb_: 5a7p B: [280230]
      automated match to d4bisa_
      complexed with 6z1, dms, edo, mn, so4, zn
  18. Domain(s) for 5a7q:
    1. 2071142Domain d5a7qa_: 5a7q A: [280222]
      automated match to d4bisa_
      complexed with cl, edo, kch, mn, zn
    2. 2071143Domain d5a7qb_: 5a7q B: [280226]
      automated match to d4bisa_
      complexed with cl, edo, kch, mn, zn
  19. Domain(s) for 5a7s:
    1. 2071146Domain d5a7sa_: 5a7s A: [280224]
      automated match to d4bisa_
      complexed with dms, edo, mn, s2x, zn
    2. 2071147Domain d5a7sb_: 5a7s B: [280225]
      automated match to d4bisa_
      complexed with dms, edo, mn, s2x, zn
  20. Domain(s) for 5a7w:
  21. Domain(s) for 5a80:
    1. 2071157Domain d5a80a_: 5a80 A: [280231]
      automated match to d4bisa_
      complexed with 9cj, edo, mn, so4, zn
    2. 2071158Domain d5a80b_: 5a80 B: [280232]
      automated match to d4bisa_
      complexed with 9cj, edo, mn, so4, zn
  22. Domain(s) for 5anq:
    1. 2269323Domain d5anqa_: 5anq A: [312629]
      automated match to d4v2wb_
      complexed with 5yq, cl, fe2, so4, zn
    2. 2269622Domain d5anqb_: 5anq B: [312927]
      automated match to d4v2wb_
      complexed with 5yq, cl, fe2, so4, zn
  23. Domain(s) for 5f2s:
    1. 2270559Domain d5f2sb_: 5f2s B: [313864]
      automated match to d4v2wb_
      complexed with 5tz, cl, dms, edo, zn
    2. 2270574Domain d5f2sd_: 5f2s D: [313879]
      automated match to d4v2wb_
      complexed with 5tz, cl, dms, edo, zn
    3. 2270653Domain d5f2sa_: 5f2s A: [313958]
      automated match to d4v2wb_
      complexed with 5tz, cl, dms, edo, zn
    4. 2270681Domain d5f2sc_: 5f2s C: [313986]
      automated match to d4v2wb_
      complexed with 5tz, cl, dms, edo, zn
  24. Domain(s) for 5f2w:
    1. 2270565Domain d5f2wc_: 5f2w C: [313870]
      automated match to d4v2wb_
      complexed with 5up, dms, edo, zn
    2. 2270596Domain d5f2wd_: 5f2w D: [313901]
      automated match to d4v2wb_
      complexed with 5up, dms, edo, zn
    3. 2270616Domain d5f2wb_: 5f2w B: [313921]
      automated match to d4v2wb_
      complexed with 5up, dms, edo, zn
    4. 2270634Domain d5f2wa_: 5f2w A: [313939]
      automated match to d4v2wb_
      complexed with 5up, dms, edo, zn
  25. Domain(s) for 5f32:
    1. 2270554Domain d5f32d_: 5f32 D: [313859]
      automated match to d4v2wb_
      complexed with 5v7, dms, edo, gol, zn
    2. 2270595Domain d5f32c_: 5f32 C: [313900]
      automated match to d4v2wb_
      complexed with 5v7, dms, edo, gol, zn
    3. 2270606Domain d5f32a_: 5f32 A: [313911]
      automated match to d4v2wb_
      complexed with 5v7, dms, edo, gol, zn
    4. 2270628Domain d5f32b_: 5f32 B: [313933]
      automated match to d4v2wb_
      complexed with 5v7, dms, edo, gol, zn
  26. Domain(s) for 5f37:
    1. 2270537Domain d5f37a_: 5f37 A: [313842]
      automated match to d4v2wb_
      complexed with dms, edo, n5j, zn
    2. 2270538Domain d5f37b_: 5f37 B: [313843]
      automated match to d4v2wb_
      complexed with dms, edo, n5j, zn
    3. 2270569Domain d5f37c_: 5f37 C: [313874]
      automated match to d4v2wb_
      complexed with dms, edo, n5j, zn
    4. 2270575Domain d5f37d_: 5f37 D: [313880]
      automated match to d4v2wb_
      complexed with dms, edo, n5j, zn
  27. Domain(s) for 5f39:
    1. 2270549Domain d5f39c_: 5f39 C: [313854]
      automated match to d4v2wb_
      complexed with 5ub, dms, zn
    2. 2270552Domain d5f39a_: 5f39 A: [313857]
      automated match to d4v2wb_
      complexed with 5ub, dms, zn
    3. 2270612Domain d5f39b_: 5f39 B: [313917]
      automated match to d4v2wb_
      complexed with 5ub, dms, zn
    4. 2270667Domain d5f39d_: 5f39 D: [313972]
      automated match to d4v2wb_
      complexed with 5ub, dms, zn
  28. Domain(s) for 5f3c:
    1. 2270545Domain d5f3cc_: 5f3c C: [313850]
      automated match to d4v2wb_
      complexed with 5u8, cl, dms, gol, zn
    2. 2270591Domain d5f3ca_: 5f3c A: [313896]
      automated match to d4v2wb_
      complexed with 5u8, cl, dms, gol, zn
    3. 2270614Domain d5f3cb_: 5f3c B: [313919]
      automated match to d4v2wb_
      complexed with 5u8, cl, dms, gol, zn
    4. 2270663Domain d5f3cd_: 5f3c D: [313968]
      automated match to d4v2wb_
      complexed with 5u8, cl, dms, gol, zn
  29. Domain(s) for 5f3e:
    1. 2270557Domain d5f3ec_: 5f3e C: [313862]
      automated match to d4v2wb_
      complexed with 5uo, dms, gol, zn
    2. 2270620Domain d5f3ed_: 5f3e D: [313925]
      automated match to d4v2wb_
      complexed with 5uo, dms, gol, zn
    3. 2270674Domain d5f3ea_: 5f3e A: [313979]
      automated match to d4v2wb_
      complexed with 5uo, dms, gol, zn
    4. 2270684Domain d5f3eb_: 5f3e B: [313989]
      automated match to d4v2wb_
      complexed with 5uo, dms, gol, zn
  30. Domain(s) for 5f3g:
    1. 2270558Domain d5f3ga_: 5f3g A: [313863]
      automated match to d4v2wb_
      complexed with 5ul, cl, dms, zn
    2. 2270560Domain d5f3gd_: 5f3g D: [313865]
      automated match to d4v2wb_
      complexed with 5ul, cl, dms, zn
    3. 2270621Domain d5f3gb_: 5f3g B: [313926]
      automated match to d4v2wb_
      complexed with 5ul, cl, dms, zn
    4. 2270669Domain d5f3gc_: 5f3g C: [313974]
      automated match to d4v2wb_
      complexed with 5ul, cl, dms, zn
  31. Domain(s) for 5f3i:
    1. 2270556Domain d5f3ic_: 5f3i C: [313861]
      automated match to d4v2wb_
      complexed with 5uj, cl, dms, gol, zn
    2. 2270562Domain d5f3ia_: 5f3i A: [313867]
      automated match to d4v2wb_
      complexed with 5uj, cl, dms, gol, zn
    3. 2270641Domain d5f3ib_: 5f3i B: [313946]
      automated match to d4v2wb_
      complexed with 5uj, cl, dms, gol, zn
    4. 2270659Domain d5f3id_: 5f3i D: [313964]
      automated match to d4v2wb_
      complexed with 5uj, cl, dms, gol, zn
  32. Domain(s) for 5f5i:
    1. 2071171Domain d5f5ia_: 5f5i A: [280148]
      automated match to d4v2wb_
      complexed with 5v1, ni, so4, zn
    2. 2071172Domain d5f5ib_: 5f5i B: [280149]
      automated match to d4v2wb_
      complexed with 5v1, ni, so4, zn
  33. Domain(s) for 5fpv:
    1. 2071163Domain d5fpva_: 5fpv A: [280435]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    2. 2071164Domain d5fpvb_: 5fpv B: [280436]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    3. 2071165Domain d5fpvc_: 5fpv C: [280434]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    4. 2071166Domain d5fpvd_: 5fpv D: [280437]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    5. 2071167Domain d5fpve_: 5fpv E: [280439]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    6. 2071168Domain d5fpvf_: 5fpv F: [280438]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    7. 2071169Domain d5fpvg_: 5fpv G: [280441]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
    8. 2071170Domain d5fpvh_: 5fpv H: [280440]
      automated match to d4v2wb_
      complexed with mmk, mn, ni, zn
  34. Domain(s) for 5fy8:
    1. 2271255Domain d5fy8b_: 5fy8 B: [314560]
      automated match to d4bisa_
      complexed with dms, edo, n81, ni, zn
    2. 2271277Domain d5fy8a_: 5fy8 A: [314582]
      automated match to d4bisa_
      complexed with dms, edo, n81, ni, zn
  35. Domain(s) for 5fyc:
    1. 2271273Domain d5fyca_: 5fyc A: [314578]
      automated match to d4bisa_
      complexed with edo, fum, ni, so4, zn
    2. 2271307Domain d5fycb_: 5fyc B: [314612]
      automated match to d4bisa_
      complexed with edo, fum, ni, so4, zn
  36. Domain(s) for 5fyh:
    1. 2271286Domain d5fyha_: 5fyh A: [314591]
      automated match to d4bisa_
      complexed with edo, fum, mn, so4, zn
    2. 2271314Domain d5fyhb_: 5fyh B: [314619]
      automated match to d4bisa_
      complexed with edo, fum, mn, so4, zn
  37. Domain(s) for 5fyi:
    1. 2271316Domain d5fyia_: 5fyi A: [314621]
      automated match to d4bisa_
      complexed with 1ka, dms, edo, ni, pyr, zn
    2. 2271323Domain d5fyib_: 5fyi B: [314628]
      automated match to d4bisa_
      complexed with 1ka, dms, edo, ni, pyr, zn
  38. Domain(s) for 5tvr:
    1. 2286023Domain d5tvra_: 5tvr A: [329324]
      automated match to d5f37b_
      complexed with akg, ni, zn
    2. 2286061Domain d5tvrb_: 5tvr B: [329362]
      automated match to d5f37b_
      complexed with akg, ni, zn
  39. Domain(s) for 5tvs:
    1. 2286015Domain d5tvsa_: 5tvs A: [329316]
      automated match to d5f37b_
      complexed with ni, zn
    2. 2286070Domain d5tvsb_: 5tvs B: [329371]
      automated match to d5f37b_
      complexed with ni, zn
  40. Domain(s) for 5vgi:
    1. 2296360Domain d5vgic_: 5vgi C: [339661]
      automated match to d4v2wb_
      complexed with 9dj, ni, zn
    2. 2296361Domain d5vgib_: 5vgi B: [339662]
      automated match to d4v2wb_
      complexed with 9dj, ni, zn
    3. 2296364Domain d5vgia_: 5vgi A: [339665]
      automated match to d4v2wb_
      complexed with 9dj, ni, zn
    4. 2296374Domain d5vgid_: 5vgi D: [339675]
      automated match to d4v2wb_
      complexed with 9dj, ni, zn
  41. Domain(s) for 5vmp:
    1. 2296371Domain d5vmpa_: 5vmp A: [339672]
      automated match to d4v2wb_
      complexed with 9fj, ni, zn
    2. 2296372Domain d5vmpb_: 5vmp B: [339673]
      automated match to d4v2wb_
      complexed with 9fj, ni, zn
    3. 2296373Domain d5vmpd_: 5vmp D: [339674]
      automated match to d4v2wb_
      complexed with 9fj, ni, zn
    4. 2296377Domain d5vmpc_: 5vmp C: [339678]
      automated match to d4v2wb_
      complexed with 9fj, ni, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from b.82.2.14 JMJD2A core

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.82.2.14 JMJD2A core: