SCOPe 2.06: Domain d4cohb_: 4coh B:

Lineage for d4cohb_ (4coh B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (64 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:5693] [196511] (10 PDB entries)

8. Domain d4cohb_: 4coh B: [238103]
   automated match to d3khma_
   complexed with hem, t9h

Details for d4cohb_

PDB Entry: 4coh, 2.08 Å

PDB Description: Crystal structure of Trypanosoma cruzi CYP51 bound to the sulfonamide derivative of the 4-aminopyridyl-based inhibitor

PDB Compounds: (B:) Sterol 14-alpha demethylase

SCOPe Domain Sequences for d4cohb_:

Sequence, based on SEQRES records:

>d4cohb_ a.104.1.0 (B:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ptdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsr
ffsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqh
evrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessl
ipaavfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllka
vyrdgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpa
qlnydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllsh
hdeeafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqll
rdevpdpdyhtmvvgptlnqclvkytrkkklp

Sequence, based on observed residues (ATOM records):

>d4cohb_ a.104.1.0 (B:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
ptdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsr
ffsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqh
evrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessl
ipaavfmpwllrlplpqsarcrearaelqkilgeiivareketsdllggllkavyrdgtr
mslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnydnv
mdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeeafp
nprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevpdp
dyhtmvvgptlnqclvkytrkkklp

Timeline for d4cohb_:

• d4cohb_ first appeared in SCOPe 2.03
  
• d4cohb_ appears in SCOPe 2.05
  
• d4cohb_ appears in SCOPe 2.07
  
• d4cohb_ appears in the current release, SCOPe 2.08