SCOPe 2.04: Domain d4cklb_: 4ckl B:

Lineage for d4cklb_ (4ckl B:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.11: Type II DNA topoisomerase C-terminal domain-like [56718] (1 superfamily)
   4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

4. Superfamily e.11.1: Type II DNA topoisomerase C-terminal domain-like [56719] (2 families)

5. Family e.11.1.1: Type II DNA topoisomerase C-terminal domain-like [56720] (3 proteins)
   domain 2 contains the catalytic tyrosine residue

6. Protein DNA Gyrase A [56723] (2 species)

7. Species Escherichia coli [TaxId:562] [56724] (5 PDB entries)

8. Domain d4cklb_: 4ckl B: [237543]
   automated match to d1ab4a_
   complexed with sm8

Details for d4cklb_

PDB Entry: 4ckl, 2.05 Å

PDB Description: Structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit with simocyclinone D8 bound

PDB Compounds: (B:) DNA gyrase subunit A

SCOPe Domain Sequences for d4cklb_:

Sequence, based on SEQRES records:

>d4cklb_ e.11.1.1 (B:) DNA Gyrase A {Escherichia coli [TaxId: 562]}
alpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydtivrm
aqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdnydgt
ekipdvmptkipnllvngssgiavgmatnipphnltevingclayiddedisieglmehi
pgpdfptaaiingrrgieeayrtgrgkvyiraraevevdaktgretiivheipyqvnkar
liekiaelvkekrvegisalrdesdkdgmrivievkrdavgevvlnnlysqtqlqvsfgi
nmvalhhgqpkimnlkdiiaafvrhrrevvtrrtifelrkardrahilealavalanidp
iielirhaptpaeaktalvanpwqlgnvaamleragddaarpewlepefgvrdglyylte
qqaqaildlrlqkltgleheklldeykelldqiaellrilgsadrlmevireelelvreq
fgdkrrteit

Sequence, based on observed residues (ATOM records):

>d4cklb_ e.11.1.1 (B:) DNA Gyrase A {Escherichia coli [TaxId: 562]}
alpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydtivrm
aqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdnydgt
ekipdvmptkipnllvngssatnipphnltevingclayiddedisieglmehipgpdfp
taaiingrrgieeayrtgrgkvyiraraevetiivheipyqvnkarliekiaelvkekrv
egisalrdesdkdgmrivieevvlnnlysqtqlqvsfginmvalhhgqpkimnlkdiiaa
fvrhrrevvtrrtifelrkardrahilealavalanidpiielinpwqlgdaarpewlep
lyylteqqaqaildlrlqklleheklldeykelldqiaellrilgsadrlmevireelel
vreqfgdkrrteit

Timeline for d4cklb_:

• d4cklb_ first appeared in SCOPe 2.03
  
• d4cklb_ appears in SCOPe 2.05
  
• d4cklb_ appears in the current release, SCOPe 2.08