PDB entry 4ckl

View 4ckl on RCSB PDB site
Description: Structure of 55 kDa N-terminal domain of E. coli DNA gyrase A subunit with simocyclinone D8 bound
Class: isomerase
Keywords: isomerase, topoisomerase, antibiotic target
Deposited on 2014-01-07, released 2014-03-12
The last revision prior to the SCOPe 2.04 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.19736
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit A
    Species: ESCHERICHIA COLI [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4ckla_
  • Chain 'B':
    Compound: DNA gyrase subunit A
    Species: ESCHERICHIA COLI [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d4cklb_
  • Heterogens: SM8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cklA (A:)
vgralpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydti
vrmaqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdny
dgtekipdvmptkipnllvngssgiavgmatnipphnltevingclayiddedisieglm
ehipgpdfptaaiingrrgieeayrtgrgkvyiraraevevdaktgretiivheipyqvn
karliekiaelvkekrvegisalrdesdkdgmrivievkrdavgevvlnnlysqtqlqvs
fginmvalhhgqpkimnlkdiiaafvrhrrevvtrrtifelrkardrahilealavalan
idpiielirhaptpaeaktalvanpwqlgnvaamleragddaarpewlepefgvrdglyy
lteqqaqaildlrlqkltgleheklldeykelldqiaellrilgsadrlmevireelelv
reqfgdkrrteit

    Sequence, based on observed residues (ATOM records): (download) 
    >4cklA (A:)
alpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydtivrm
aqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdnydgt
ekipdvmptkipnllvngssgiatnipphnltevingclayiddedisieglmehipgpd
fptaaiingrrgieeayrtgrgkvyirariivheipyqvnkarliekiaelvklrdesdk
dgmrivivvlnnlysqtqlqvsfginmvalhhgqpkimnlkdiiaafvrhrrevvtrrti
felrkardrahilealavalanidpiielirhaptpaeaktalvanpwqlgnvaamleda
arpewlepefgvrdglyylteqqaqaildlrlqkltgleheklldeykelldqiaellri
lgsadrlmevireelelvreqfgdkrrtei

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4cklB (B:)
vgralpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydti
vrmaqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdny
dgtekipdvmptkipnllvngssgiavgmatnipphnltevingclayiddedisieglm
ehipgpdfptaaiingrrgieeayrtgrgkvyiraraevevdaktgretiivheipyqvn
karliekiaelvkekrvegisalrdesdkdgmrivievkrdavgevvlnnlysqtqlqvs
fginmvalhhgqpkimnlkdiiaafvrhrrevvtrrtifelrkardrahilealavalan
idpiielirhaptpaeaktalvanpwqlgnvaamleragddaarpewlepefgvrdglyy
lteqqaqaildlrlqkltgleheklldeykelldqiaellrilgsadrlmevireelelv
reqfgdkrrteit

    Sequence, based on observed residues (ATOM records): (download) 
    >4cklB (B:)
alpdvrdglkpvhrrvlyamnvlgndwnkaykksarvvgdvigkyhphgdsavydtivrm
aqpfslrymlvdgqgnfgsidgdsaaamryteirlakiahelmadleketvdfvdnydgt
ekipdvmptkipnllvngssatnipphnltevingclayiddedisieglmehipgpdfp
taaiingrrgieeayrtgrgkvyiraraevetiivheipyqvnkarliekiaelvkekrv
egisalrdesdkdgmrivieevvlnnlysqtqlqvsfginmvalhhgqpkimnlkdiiaa
fvrhrrevvtrrtifelrkardrahilealavalanidpiielinpwqlgdaarpewlep
lyylteqqaqaildlrlqklleheklldeykelldqiaellrilgsadrlmevireelel
vreqfgdkrrteit