SCOPe 2.05: Domain d4aota_: 4aot A:

Lineage for d4aota_ (4aot A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)

8. Domain d4aota_: 4aot A: [234091]
   automated match to d4equb_
   complexed with cl, gw8

Details for d4aota_

PDB Entry: 4aot, 2.33 Å

PDB Description: crystal structure of human serine threonine kinase-10 (lok) bound to gw830263a

PDB Compounds: (A:) serine/threonine-protein kinase 10

SCOPe Domain Sequences for d4aota_:

Sequence, based on SEQRES records:

>d4aota_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrksreyehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeel
edyiveieilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiq
vvcrqmlealnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigt
pywmapevvmcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllkiaksdpp
tlltpskwsvefrdflkialdknpetrpsaaqllehpfvssitsnkalrelvaeakaev

Sequence, based on observed residues (ATOM records):

>d4aota_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrksreyehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeel
edyiveieilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiq
vvcrqmlealnflhskriihrdlkagnvlmtlegdirladfgvsagtpywmapevvmydy
kadiwslgitliemaqiepphhelnpmrvllkiaksdpptlltpskwsvefrdflkiald
knpetrpsaaqllehpfvssitsnkalrelvaeakaev

Timeline for d4aota_:

• d4aota_ first appeared in SCOPe 2.03
  
• d4aota_ appears in SCOPe 2.04
  
• d4aota_ is called d4aota1 in SCOPe 2.06
  
• d4aota_ appears in the current release, SCOPe 2.08, called d4aota1