SCOP 1.75: Domain d1rsya_: 1rsy A:

Lineage for d1rsya_ (1rsy A:)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)
   two constituent families are related by circular permutation

5. Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (10 proteins)
   topologically similar to the C-terminal domain of PapD

6. Protein Synaptogamin I [49576] (2 species)
   duplication: contains tandem repeat of two similar domains

7. Species Rat (Rattus norvegicus) [TaxId:10116] [49577] (7 PDB entries)
   Uniprot P21707 271-419
   Uniprot P21707 271-419
   Uniprot P21707 271-419 ! Uniprot P21707 271-419

8. Domain d1rsya_: 1rsy A: [23192]
   first C2 domain
   CASP1
   complexed with so4

Details for d1rsya_

PDB Entry: 1rsy, 1.9 Å

PDB Description: structure of the first c2-domain of synaptotagmin i: a novel ca2+(slash)phospholipid binding fold

PDB Compounds: (A:) Synaptotagmin I

SCOP Domain Sequences for d1rsya_:

Sequence, based on SEQRES records:

>d1rsya_ b.7.1.2 (A:) Synaptogamin I {Rat (Rattus norvegicus) [TaxId: 10116]}
gggildsmvekeepkeeeklgklqysldydfqnnqllvgiiqaaelpaldmggtsdpyvk
vfllpdkkkkfetkvhrktlnpvfneqftfkvpyselggktlvmavydfdrfskhdiige
fkvpmntvdfghvteewrdlqsa

Sequence, based on observed residues (ATOM records):

>d1rsya_ b.7.1.2 (A:) Synaptogamin I {Rat (Rattus norvegicus) [TaxId: 10116]}
gggildsmveklgklqysldydfqnnqllvgiiqaaelpaldmggtsdpyvkvfllpdkk
kkfetkvhrktlnpvfneqftfkvpyselggktlvmavydfdrfskhdiigefkvpmntv
dfghvteewrdlqsa

Timeline for d1rsya_:

• d1rsya_ first appeared (with stable ids) in SCOP 1.55, called d1rsy__
  
• d1rsya_ appears in SCOP 1.73
  
• d1rsya_ appears in SCOPe 2.01
  
• d1rsya_ appears in the current release, SCOPe 2.08, called d1rsya1