SCOPe 2.07: Domain d2qepb1: 2qep B:724-1010

Lineage for d2qepb1 (2qep B:724-1010)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d2qepb1: 2qep B:724-1010 [231204]
   Other proteins in same PDB: d2qepa2, d2qepb2
   automated match to d2i1yb_
   complexed with cl

Details for d2qepb1

PDB Entry: 2qep, 2.5 Å

PDB Description: crystal structure of the d1 domain of ptprn2 (ia2beta)

PDB Compounds: (B:) Receptor-type tyrosine-protein phosphatase N2

SCOPe Domain Sequences for d2qepb1:

Sequence, based on SEQRES records:

>d2qepb1 c.45.1.0 (B:724-1010) automated matches {Human (Homo sapiens) [TaxId: 9606]}
distghmilsymedhlknknrlekewealcayqaepnssfvaqreenvpknrslavltyd
hsrvllkaenshshsdyinaspimdhdprnpayiatqgplpatvadfwqmvwesgcvviv
mltplaengvrqcyhywpdegsnlyhiyevnlvsehiwcedflvrsfylknlqtnetrtv
tqfhflswydrgvpsssrslldfrrkvnkcyrgrscpiivhcsdgagrsgtyvlidmvln
kmakgakeidiaatlehlrdqrpgmvqtkeqfefaltavaeevnail

Sequence, based on observed residues (ATOM records):

>d2qepb1 c.45.1.0 (B:724-1010) automated matches {Human (Homo sapiens) [TaxId: 9606]}
distghmilsymedhlknknrlekewealcayqaepnssfvaqreenvpknrslavltyd
hsrvllkaenshshsdyinaspimddprnpayiatqgplpatvadfwqmvwesgcvvivm
ltplaengvrqcyhywpdegsnlyhiyevnlvsehiwcedflvrsfylknlqtnetrtvt
qfhflswydrgvpsssrslldfrrkvnkcyrgrscpiivhcsdgagrsgtyvlidmvlnk
makgkeidiaatlehlrdqrpgmvqtkeqfefaltavaeevnail

Timeline for d2qepb1:

• d2qepb1 first appeared in SCOPe 2.03, called d2qepb_
  
• d2qepb1 appears in SCOPe 2.06
  
• d2qepb1 appears in the current release, SCOPe 2.08