SCOPe 2.05: Domain d4jzfh_: 4jzf H:

Lineage for d4jzfh_ (4jzf H:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (50 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d4jzfh_: 4jzf H: [227611]
   Other proteins in same PDB: d4jzfl_
   automated match to d1klih_
   complexed with 1nl, ca, gol, so4

Details for d4jzfh_

PDB Entry: 4jzf, 1.84 Å

PDB Description: Structure of factor VIIA in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2S)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid

PDB Compounds: (H:) Factor VIIa (Heavy Chain)

SCOPe Domain Sequences for d4jzfh_:

Sequence; same for both SEQRES and ATOM records:

>d4jzfh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d4jzfh_:

• d4jzfh_ first appeared in SCOPe 2.03
  
• d4jzfh_ appears in SCOPe 2.04
  
• d4jzfh_ appears in SCOPe 2.06
  
• d4jzfh_ appears in the current release, SCOPe 2.08