SCOPe 2.07: Domain d4foea3: 4foe A:466-670

Lineage for d4foea3 (4foe A:466-670)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.1: Actin-like ATPase domain [53067] (16 families)
   duplication contains two domains of this fold

5. Family c.55.1.3: Hexokinase [53083] (3 proteins)

6. Protein Mammalian type I hexokinase [53086] (2 species)
   further duplication: consists of two very similar lobes

7. Species Human (Homo sapiens) [TaxId:9606] [53087] (10 PDB entries)

8. Domain d4foea3: 4foe A:466-670 [221395]
   automated match to d1hkba3
   complexed with bgc, cit, m6d, na

Details for d4foea3

PDB Entry: 4foe, 2.7 Å

PDB Description: crystal structure of recombinant human hexokinase type i with mannose 6-phosphate

PDB Compounds: (A:) Hexokinase-1

SCOPe Domain Sequences for d4foea3:

Sequence; same for both SEQRES and ATOM records:

>d4foea3 c.55.1.3 (A:466-670) Mammalian type I hexokinase {Human (Homo sapiens) [TaxId: 9606]}
qhrqieetlahfhltkdmllevkkrmraemelglrkqthnnavvkmlpsfvrrtpdgten
gdflaldlggtnfrvllvkirsgkkrtvemhnkiyaipieimqgtgeelfdhivscisdf
ldymgikgprmplgftfsfpcqqtsldagilitwtkgfkatdcvghdvvtllrdaikrre
efdldvvavvndtvgtmmtcayeep

Timeline for d4foea3:

• d4foea3 first appeared in SCOPe 2.03
  
• d4foea3 appears in SCOPe 2.06
  
• d4foea3 appears in the current release, SCOPe 2.08