SCOPe 2.07: Family c.55.1.3: Hexokinase

Lineage for Family c.55.1.3: Hexokinase

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.1: Actin-like ATPase domain [53067] (16 families)
   duplication contains two domains of this fold

5. Family c.55.1.3: Hexokinase [53083] (3 proteins)

Proteins:

1. Glucokinase [102479] (1 species)
   Hexokinase D

   • Species Human (Homo sapiens) [TaxId:9606] [102480] (6 PDB entries)

2. Hexokinase [53084] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae), pII [TaxId:4932] [64092] (1 PDB entry)

   2. Species Blood fluke (Schistosoma mansoni) [TaxId:6183] [53085] (1 PDB entry)

3. Mammalian type I hexokinase [53086] (2 species)
   further duplication: consists of two very similar lobes

   1. Species Human (Homo sapiens) [TaxId:9606] [53087] (10 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [53088] (1 PDB entry)

More info for Family c.55.1.3: Hexokinase

Timeline for Family c.55.1.3: Hexokinase:

• Family c.55.1.3: Hexokinase first appeared (with stable ids) in SCOP 1.55
  
• Family c.55.1.3: Hexokinase appears in SCOPe 2.06
  
• Family c.55.1.3: Hexokinase appears in the current release, SCOPe 2.08