SCOPe 2.07: Domain d3hqpi1: 3hqp I:1-87,I:187-357

Lineage for d3hqpi1 (3hqp I:1-87,I:187-357)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.1: Pyruvate kinase [51622] (1 protein)

6. Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
   this domain is interrupted by an all-beta domain
   C-terminal domain is alpha/beta

7. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [51626] (11 PDB entries)

8. Domain d3hqpi1: 3hqp I:1-87,I:187-357 [211254]
   Other proteins in same PDB: d3hqpa2, d3hqpa3, d3hqpb2, d3hqpb3, d3hqpc2, d3hqpc3, d3hqpd2, d3hqpd3, d3hqpe2, d3hqpe3, d3hqpf2, d3hqpf3, d3hqpg2, d3hqpg3, d3hqph2, d3hqph3, d3hqpi2, d3hqpi3, d3hqpj2, d3hqpj3, d3hqpk2, d3hqpk3, d3hqpl2, d3hqpl3, d3hqpm2, d3hqpm3, d3hqpn2, d3hqpn3, d3hqpo2, d3hqpo3, d3hqpp2, d3hqpp3
   automated match to d1pkla2
   complexed with atp, fdp, gol, k, mg, oxl

Details for d3hqpi1

PDB Entry: 3hqp, 2.3 Å

PDB Description: crystal structure of leishmania mexicana pyruvate kinase (lmpyk) in complex with atp, oxalate and fructose 2,6 bisphosphate

PDB Compounds: (I:) pyruvate kinase

SCOPe Domain Sequences for d3hqpi1:

Sequence; same for both SEQRES and ATOM records:

>d3hqpi1 c.1.12.1 (I:1-87,I:187-357) Pyruvate kinase, N-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}
sqlahnltlsifdpvanyraariictigpstqsvealkgliqsgmsvarmnfshgsheyh
qttinnvrqaaaelgvniaialdtkgpXpavsakdrvdlqfgveqgvdmifasfirsaeq
vgdvrkalgpkgrdimiickienhqgvqnidsiieesdgimvargdlgveipaekvvvaq
kiliskcnvagkpvicatqmlesmtynprptraevsdvanavfngadcvmlsgetakgky
pnevvqymaricleaqsal

Timeline for d3hqpi1:

• d3hqpi1 first appeared in SCOPe 2.03
  
• d3hqpi1 appears in SCOPe 2.06
  
• d3hqpi1 appears in the current release, SCOPe 2.08