SCOP 1.69: Domain d1fvec2: 1fve C:108-214

Lineage for d1fvec2 (1fve C:108-214)

Root: SCOP 1.69
Class b: All beta proteins [48724] (144 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (4 families)
Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)
Species Human (Homo sapiens) [TaxId:9606] [88569] (78 PDB entries)
including humanized antibodies (chimeric proteins with human constant domains)
Domain d1fvec2: 1fve C:108-214 [20968]
Other proteins in same PDB: d1fvea1, d1fveb1, d1fveb2, d1fvec1, d1fved1, d1fved2
part of humanized Fab 4D5, herceptin

Details for d1fvec2

PDB Entry: 1fve (more details), 2.7 Å

PDB Description: x-ray structures of the antigen-binding domains from three variants of humanized anti-p185-her2 antibody 4d5 and comparison with molecular modeling

SCOP Domain Sequences for d1fvec2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fvec2 b.1.1.2 (C:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOP Domain Coordinates for d1fvec2:

Click to download the PDB-style file with coordinates for d1fvec2.
(The format of our PDB-style files is described here.)

Timeline for d1fvec2: