SCOPe 2.07: Domain d2od9a1: 2od9 A:1-293

Lineage for d2od9a1 (2od9 A:1-293)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
   silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain

6. Protein automated matches [191258] (3 species)
   not a true protein

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [225225] (2 PDB entries)

8. Domain d2od9a1: 2od9 A:1-293 [205251]
   Other proteins in same PDB: d2od9a2
   automated match to d1q17c_
   complexed with a1r, nca, zn

Details for d2od9a1

PDB Entry: 2od9, 2.05 Å

PDB Description: structural basis for nicotinamide inhibition and base exchange in sir2 enzymes

PDB Compounds: (A:) NAD-dependent deacetylase HST2

SCOPe Domain Sequences for d2od9a1:

Sequence, based on SEQRES records:

>d2od9a1 c.31.1.5 (A:1-293) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
msvstastemsvrkiaahmksnpnakvifmvgagistscgipdfrspgtglyhnlarlkl
pypeavfdvdffqsdplpfytlakelypgnfrpskfhyllklfqdkdvlkrvytqnidtl
erqagvkddliieahgsfahchcigcgkvyppqvfksklaehpikdfvkcdvcgelvkpa
ivffgedlpdsfsetwlndsewlrekittsgkhpqqplvivvgtslavypfaslpeeipr
kvkrvlcnletvgdfkankrptdlivhqysdefaeqlveelgwqedfekilta

Sequence, based on observed residues (ATOM records):

>d2od9a1 c.31.1.5 (A:1-293) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
msvstastemsvrkiaahmksnpnakvifmvgagistscgipdfrspgtglyhnlarlkl
pypeavfdvdffqsdplpfytlakelypgnfrpskfhyllklfqdkdvlkrvytqnidtl
erqagvkddliieahgsfahchcigcgkvyppqvfksklaehpikdfvkcdvcgelvkpa
ivffgedlpdsfsetwlndsewlrekittqqplvivvgtslavypfaslpeeiprkvkrv
lcnletvgdfkankrptdlivhqysdefaeqlveelgwqedfekilta

Timeline for d2od9a1:

• d2od9a1 first appeared in SCOPe 2.03, called d2od9a_
  
• d2od9a1 appears in SCOPe 2.06
  
• d2od9a1 appears in the current release, SCOPe 2.08