SCOPe 2.04: Domain d2ewda2: 2ewd A:165-333

Lineage for d2ewda2 (2ewd A:165-333)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (19 species)

7. Species Cryptosporidium parvum [TaxId:5807] [225186] (4 PDB entries)

8. Domain d2ewda2: 2ewd A:165-333 [204146]
   Other proteins in same PDB: d2ewda1, d2ewdb1
   automated match to d1ez4a2
   complexed with a3d, gol, pyr

Details for d2ewda2

PDB Entry: 2ewd, 2 Å

PDB Description: Crystal structure of the Lactate Dehydrogenase from Cryptosporidium parvum complexed with substrate (Pyruvic acid) and cofactor analog (3-Acetylpyridine adenine dinucleotide).

PDB Compounds: (A:) lactate dehydrogenase,

SCOPe Domain Sequences for d2ewda2:

Sequence; same for both SEQRES and ATOM records:

>d2ewda2 d.162.1.1 (A:165-333) Lactate dehydrogenase {Cryptosporidium parvum [TaxId: 5807]}
gvldssrfrtfiaqhfgvnasdvsanvigghgdgmvpatssvsvggvplssfikqglitq
eqideivchtriawkevadnlktgtayfapaaaavkmaeaylkdkkavvpcsafcsnhyg
vkgiymgvptiigkngvedileldltpleqkllgesinevntiskvldnap

Timeline for d2ewda2:

• d2ewda2 first appeared in SCOPe 2.03
  
• d2ewda2 does not appear in SCOPe 2.05