Lineage for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1680346Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 1680347Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 1680348Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866

Proteins:

  1. 1680349L-2-hydroxyisocapronate dehydrogenase, L-HICDH [56337] (1 species)
  2. 1680355Lactate dehydrogenase [56339] (19 species)
    1. Species Archaeoglobus fulgidus [TaxId:2234] [111253] (2 PDB entries)
      Uniprot O08349
    2. 1680359Species Bacillus stearothermophilus [TaxId:1422] [56344] (3 PDB entries)
    3. 1680376Species Bifidobacterium longum, strain am101-2 [TaxId:216816] [56346] (2 PDB entries)
    4. 1680381Species Clostridium thermocellum [TaxId:1515] [118160] (1 PDB entry)
      Uniprot Q4CDK5
    5. 1680383Species Cryptosporidium parvum [TaxId:5807] [225186] (4 PDB entries)
    6. 1680394Species Dogfish (Squalus acanthias) [TaxId:7797] [56342] (3 PDB entries)
    7. 1680398Species Homo sapiens [TaxId:9606] [256978] (1 PDB entry)
    8. 1680400Species Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [64444] (2 PDB entries)
    9. 1680407Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (7 PDB entries)
    10. 1680437Species Lactobacillus casei [TaxId:1582] [56345] (6 PDB entries)
    11. 1680467Species Lactobacillus pentosus [TaxId:1589] [69843] (1 PDB entry)
    12. 1680472Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [56343] (13 PDB entries)
    13. 1680489Species Mouse (Mus musculus) [TaxId:10090] [56341] (1 PDB entry)
    14. 1680494Species Pig (Sus scrofa) [TaxId:9823] [56340] (3 PDB entries)
    15. 1680501Species Plasmodium berghei [TaxId:5821] [103325] (1 PDB entry)
    16. 1680504Species Plasmodium vivax [TaxId:5855] [225044] (2 PDB entries)
    17. 1680513Species Thermotoga maritima [TaxId:2336] [56347] (1 PDB entry)
    18. 1680515Species Thermus caldophilus [TaxId:272] [226615] (2 PDB entries)
    19. 1680524Species Toxoplasma gondii [TaxId:5811] [103326] (5 PDB entries)
  3. 1680540Malate dehydrogenase [56329] (12 species)
    1. 1680541Species Aquaspirillum arcticum [TaxId:87645] [56336] (3 PDB entries)
    2. 1680545Species Chlorobium tepidum [TaxId:1097] [69841] (1 PDB entry)
    3. 1680548Species Chlorobium vibrioforme [TaxId:1098] [69842] (2 PDB entries)
    4. 1680557Species Chloroflexus aurantiacus [TaxId:1108] [69840] (7 PDB entries)
      Uniprot P80040
    5. 1680572Species Chloroflexus sp. [TaxId:480224] [236535] (1 PDB entry)
    6. 1680575Species Escherichia coli [TaxId:562] [56333] (4 PDB entries)
    7. 1680586Species Flaveria bidentis, chloroplast [TaxId:4224] [56332] (1 PDB entry)
    8. 1680588Species Haloarcula marismortui [TaxId:2238] [56335] (5 PDB entries)
    9. 1680601Species Pig (Sus scrofa) [TaxId:9823] [56330] (3 PDB entries)
    10. 1680610Species Sorghum (Sorghum vulgare), chloroplast [TaxId:4558] [56331] (1 PDB entry)
    11. 1680615Species Thermus flavus [TaxId:274] [56334] (2 PDB entries)
    12. 1680620Species Thermus thermophilus [TaxId:274] [82806] (7 PDB entries)
      identical sequence to that from the Thermus flavus enzyme
  4. 1680635MJ0490, lactate/malate dehydrogenase [64446] (1 species)
  5. 1680640automated matches [226882] (8 species)
    not a true protein
    1. 1680641Species Cryptosporidium parvum [TaxId:353152] [261800] (5 PDB entries)
    2. 1680653Species Escherichia coli K-12 [TaxId:83333] [225274] (2 PDB entries)
    3. 1680662Species Haloarcula marismortui [TaxId:2238] [225148] (4 PDB entries)
    4. 1680679Species Human (Homo sapiens) [TaxId:9606] [225057] (2 PDB entries)
    5. 1680688Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [254909] (5 PDB entries)
    6. 1680694Species Norway rat (Rattus norvegicus) [TaxId:10116] [226330] (12 PDB entries)
    7. 1680743Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [225719] (5 PDB entries)
    8. 1680784Species Toxoplasma gondii [TaxId:5811] [233101] (1 PDB entry)

More info for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain

Timeline for Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain: