SCOPe 2.04: Domain d3zwta_: 3zwt A:

Lineage for d3zwta_ (3zwt A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)

8. Domain d3zwta_: 3zwt A: [195028]
   automated match to d1d3ga_
   complexed with act, cl, fmn, kfz, oro, so4

Details for d3zwta_

PDB Entry: 3zwt, 1.55 Å

PDB Description: Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor

PDB Compounds: (A:) Dihydroorotate dehydrogenase (quinone), mitochondrial

SCOPe Domain Sequences for d3zwta_:

Sequence, based on SEQRES records:

>d3zwta_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpvgiaagfdk
hgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvvehr
lrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntag
lrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidgl
ivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgq
dalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

Sequence, based on observed residues (ATOM records):

>d3zwta_ c.1.4.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hlmptlqglldpesahrlavrftslgllrfqdsdmlevrvlghkfrnpvgiaagfdkhge
avdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvvehrlra
rqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntaglrs
lqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidglivt
nttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgqdal
ekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

Timeline for d3zwta_:

• d3zwta_ first appeared in SCOPe 2.02
  
• d3zwta_ appears in SCOPe 2.03
  
• d3zwta_ appears in SCOPe 2.05
  
• d3zwta_ appears in the current release, SCOPe 2.08