SCOPe 2.02: Domain d3umsa2: 3ums A:6-60,A:182-354

Lineage for d3umsa2 (3ums A:6-60,A:182-354)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Transducin (alpha subunit) [52623] (4 species)
   common fold is interrupted with an all-alpha domain

7. Species Human (Homo sapiens) [TaxId:9606] [159560] (7 PDB entries)

8. Domain d3umsa2: 3ums A:6-60,A:182-354 [192181]
   Other proteins in same PDB: d3umsa1
   complexed with cl, gdp, so4; mutant

Details for d3umsa2

PDB Entry: 3ums, 2.34 Å

PDB Description: Crystal structure of the G202A mutant of human G-alpha-i1

PDB Compounds: (A:) Guanine nucleotide-binding protein G(i) subunit alpha-1

SCOPe Domain Sequences for d3umsa2:

Sequence, based on SEQRES records:

>d3umsa2 c.37.1.8 (A:6-60,A:182-354) Transducin (alpha subunit) {Human (Homo sapiens) [TaxId: 9606]}
saedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagXtgiv
ethftfkdlhfkmfdvagqrserkkwihcfegvtaiifcvalsdydlvlaedeemnrmhe
smklfdsicnnkwftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqc
qfedlnkrkdtkeiythftcatdtknvqfvfdavtdviiknnlkdcglf

Sequence, based on observed residues (ATOM records):

>d3umsa2 c.37.1.8 (A:6-60,A:182-354) Transducin (alpha subunit) {Human (Homo sapiens) [TaxId: 9606]}
saedkaaverskmidrnlredgekaarevkllllgagesgkstivkqmkiiheagXtgiv
ethftfkdlhfkmfdvafegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnk
wftdtsiilflnkkdlfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtk
eiythftcatdtknvqfvfdavtdviiknnlkdcglf

Timeline for d3umsa2:

• d3umsa2 is new in SCOPe 2.02-stable
  
• d3umsa2 appears in SCOPe 2.03
  
• d3umsa2 appears in the current release, SCOPe 2.08