SCOP 1.69: Domain d1sig__: 1sig -

Lineage for d1sig__ (1sig -)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.177: Sigma2 domain of RNA polymerase sigma factors [88945] (1 superfamily)
   multihelical; consists of a conserved 4-helical core and a variable insert subdomain

4. Superfamily a.177.1: Sigma2 domain of RNA polymerase sigma factors [88946] (1 family)

5. Family a.177.1.1: Sigma2 domain of RNA polymerase sigma factors [88947] (5 proteins)

6. Protein Sigma70 [88948] (2 species)

7. Species Escherichia coli [TaxId:562] [48332] (1 PDB entry)

8. Domain d1sig__: 1sig - [19068]
   sigma2 domain only with a large insert subdomain

Details for d1sig__

PDB Entry: 1sig, 2.6 Å

PDB Description: crystal structure of a sigma70 subunit fragment from escherichia coli rna polymerase

SCOP Domain Sequences for d1sig__:

Sequence, based on SEQRES records:

>d1sig__ a.177.1.1 (-) Sigma70 {Escherichia coli}
megeidiakriedginqvqcsvaeypeaitylleqynrveaeearlsdlitgfvdpnaee
dlaptathvgselsqedldddededeedgdddsadddnsidpelarekfaelraqyvvtr
dtikakgrshataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcv
eqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetg
ltieqvkdinrrmsigeakarrakkemveanlrlvisiakkytnrglqfldliqegnigl
mkavdkfeyrrgykfstyatwwirqaitrsiadq

Sequence, based on observed residues (ATOM records):

>d1sig__ a.177.1.1 (-) Sigma70 {Escherichia coli}
megeidiakriedginqvqcsvaeypeaitylleqynrveaeearlsdlitgfvddlapt
athvgselsqedldidpelarekfaelraqyvvtrdtikahataqeeilklsevfkqfrl
vpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaia
mnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemve
anlrlvisiakkytnrglqfldliqegniglmkavdkfeyrrgykfstyatwwirqaitr
siadq

Timeline for d1sig__:

• d1sig__ first appeared (with stable ids) in SCOP 1.55
  
• d1sig__ appears in SCOP 1.67
  
• d1sig__ appears in SCOP 1.71
  
• d1sig__ appears in the current release, SCOPe 2.08, called d1siga1