SCOPe 2.01: Domain d3qqub_: 3qqu B:

Lineage for d3qqub_ (3qqu B:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Insulin-like growth factor 1 receptor [69825] (1 species)
   PTK group; InsR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [69826] (15 PDB entries)

8. Domain d3qqub_: 3qqu B: [184587]
   automated match to d1jqha_
   complexed with 01p

Details for d3qqub_

PDB Entry: 3qqu, 2.9 Å

PDB Description: Cocrystal structure of unphosphorylated igf with pyrimidine 8

PDB Compounds: (B:) insulin-like growth factor 1 receptor

SCOPe Domain Sequences for d3qqub_:

Sequence, based on SEQRES records:

>d3qqub_ d.144.1.7 (B:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
vpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerief
lneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvlapp
slskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyr
kggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvme
gglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

Sequence, based on observed residues (ATOM records):

>d3qqub_ d.144.1.7 (B:) Insulin-like growth factor 1 receptor {Human (Homo sapiens) [TaxId: 9606]}
vpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerief
lneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpslskmiqmage
iadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllpvrw
mspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpdncp
dmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

Timeline for d3qqub_:

• d3qqub_ is new in SCOPe 2.01-stable
  
• d3qqub_ appears in SCOPe 2.02
  
• d3qqub_ appears in the current release, SCOPe 2.08