Lineage for d3n4ca_ (3n4c A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2497139Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2497140Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2497141Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2497241Protein (Pro)cathepsin S [82566] (1 species)
  7. 2497242Species Human (Homo sapiens) [TaxId:9606] [82567] (28 PDB entries)
  8. 2497267Domain d3n4ca_: 3n4c A: [181889]
    automated match to d1ms6a_
    complexed with dms, ef3, so4

Details for d3n4ca_

PDB Entry: 3n4c (more details), 1.9 Å

PDB Description: 6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors
PDB Compounds: (A:) cathepsin S

SCOPe Domain Sequences for d3n4ca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3n4ca_ d.3.1.1 (A:) (Pro)cathepsin S {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3n4ca_:

Click to download the PDB-style file with coordinates for d3n4ca_.
(The format of our PDB-style files is described here.)

Timeline for d3n4ca_: