SCOPe 2.02: Domain d3kl6b_: 3kl6 B:

Lineage for d3kl6b_ (3kl6 B:)

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (64 PDB entries)
   Uniprot P00742 127-178

8. Domain d3kl6b_: 3kl6 B: [179424]
   Other proteins in same PDB: d3kl6a_
   automated match to d1g2lb_
   complexed with 443, ca, edo

Details for d3kl6b_

PDB Entry: 3kl6, 1.45 Å

PDB Description: Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor

PDB Compounds: (B:) coagulation factor x light chain

SCOPe Domain Sequences for d3kl6b_:

Sequence; same for both SEQRES and ATOM records:

>d3kl6b_ g.3.11.1 (B:) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqt

Timeline for d3kl6b_:

• d3kl6b_ first appeared in SCOPe 2.01
  
• d3kl6b_ appears in SCOPe 2.03
  
• d3kl6b_ appears in the current release, SCOPe 2.08