SCOPe 2.02: Domain d3kgfb_: 3kgf B:

Lineage for d3kgfb_ (3kgf B:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins)
   Pfam PF01474

6. Protein Probable DAHP synthetase AroG, phenylalanine-repressible [141841] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141842] (4 PDB entries)
   Uniprot O53512 1-462

8. Domain d3kgfb_: 3kgf B: [179355]
   automated match to d2b7oa1
   complexed with cl, gol, mn, phe, po4, so4, trp

Details for d3kgfb_

PDB Entry: 3kgf, 2 Å

PDB Description: The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan

PDB Compounds: (B:) Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG

SCOPe Domain Sequences for d3kgfb_:

Sequence, based on SEQRES records:

>d3kgfb_ c.1.10.8 (B:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

Sequence, based on observed residues (ATOM records):

>d3kgfb_ c.1.10.8 (B:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipilpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtvpseiv
rlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmpvvkva
riagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaamnlvra
ltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqtaeiya
shealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvianpvgv
klgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviwqc
dpmhgnthesfktrhfdrivdevqgffevhralgthpggihveitgenvteclggaqdis
etdlagryetacdprlntqqslelaflvaemlrd

Timeline for d3kgfb_:

• d3kgfb_ first appeared in SCOPe 2.01
  
• d3kgfb_ appears in SCOPe 2.03
  
• d3kgfb_ appears in the current release, SCOPe 2.08