SCOPe 2.05: Domain d3kdub_: 3kdu B:

Lineage for d3kdub_ (3kdu B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69110] (15 PDB entries)

8. Domain d3kdub_: 3kdu B: [179297]
   automated match to d1i7ga_
   protein/DNA complex; complexed with nks

Details for d3kdub_

PDB Entry: 3kdu, 2.07 Å

PDB Description: Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine

PDB Compounds: (B:) Peroxisome proliferator-activated receptor alpha

SCOPe Domain Sequences for d3kdub_:

Sequence, based on SEQRES records:

>d3kdub_ a.123.1.1 (B:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
shmedsetadlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaek
tlvaklvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkyg
vyeaifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnaleldd
sdislfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmad
lrqlvtehaqlvqiikktesdaalhpllqeiyrdmy

Sequence, based on observed residues (ATOM records):

>d3kdub_ a.123.1.1 (B:) Peroxisome proliferator activated receptor alpha, PPAR-alpha {Human (Homo sapiens) [TaxId: 9606]}
shmedsetadlkslakriyeaylknfnmnkvkarvilsgkannppfvihdmetlcmaekt
lvvangiqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyea
ifamlssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdis
lfvaaiiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrql
vtehaqlvqiikktesdaalhpllqeiyrdmy

Timeline for d3kdub_:

• d3kdub_ first appeared in SCOPe 2.01
  
• d3kdub_ appears in SCOPe 2.04
  
• d3kdub_ is called d3kdub1 in SCOPe 2.06
  
• d3kdub_ appears in the current release, SCOPe 2.08, called d3kdub1