SCOPe 2.08: Domain d1agsa1: 1ags A:80-221

Lineage for d1agsa1 (1ags A:80-221)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.45: GST C-terminal domain-like [47615] (1 superfamily)
   core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix

4. Superfamily a.45.1: GST C-terminal domain-like [47616] (3 families)
   this domains follows the thioredoxin-like N-terminal domain

5. Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (19 proteins)

6. Protein Class alpha GST [81349] (8 species)

7. Species Human (Homo sapiens), (a1-1) [TaxId:9606] [47625] (35 PDB entries)
   Uniprot P08263

8. Domain d1agsa1: 1ags A:80-221 [17691]
   Other proteins in same PDB: d1agsa2, d1agsb2
   complexed with gtx; mutant

Details for d1agsa1

PDB Entry: 1ags, 2.5 Å

PDB Description: a surface mutant (g82r) of a human alpha-glutathione s-transferase shows decreased thermal stability and a new mode of molecular association in the crystal

PDB Compounds: (A:) glutathione s-transferase alpha

SCOPe Domain Sequences for d1agsa1:

Sequence; same for both SEQRES and ATOM records:

>d1agsa1 a.45.1.1 (A:80-221) Class alpha GST {Human (Homo sapiens), (a1-1) [TaxId: 9606]}
lyrkdikekalidmyiegiadlgemilllpftqpeeqdaklalikekiknryfpafekvl
kshgqdylvgnklsradihlvellyyveeldsslissfpllkalktrisnlptvkkflqp
gsprkppmdeksleearkifrf

Timeline for d1agsa1:

• d1agsa1 first appeared (with stable ids) in SCOP 1.55
  
• d1agsa1 appears in SCOPe 2.07