SCOPe 2.01: Domain d2y3za_: 2y3z A:

Lineage for d2y3za_ (2y3z A:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
   the active site is between the two identical subunits

6. Protein automated matches [190072] (9 species)
   not a true protein

7. Species Thermus thermophilus [TaxId:274] [189081] (5 PDB entries)

8. Domain d2y3za_: 2y3z A: [170580]
   automated match to d1g2ua_
   complexed with 2pe, gol, trs

Details for d2y3za_

PDB Entry: 2y3z, 1.83 Å

PDB Description: Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme

PDB Compounds: (A:) 3-isopropylmalate dehydrogenase

SCOPe Domain Sequences for d2y3za_:

Sequence; same for both SEQRES and ATOM records:

>d2y3za_ c.77.1.1 (A:) automated matches {Thermus thermophilus [TaxId: 274]}
smkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrk
gveeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplk
eeiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafeaarkrrkh
vvsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnif
gdilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammle
hafglvelarkvedavakalletpppdlggsagteaftatvlrhlaaaale

Timeline for d2y3za_:

• d2y3za_ is new in SCOPe 2.01-stable
  
• d2y3za_ appears in SCOPe 2.02
  
• d2y3za_ appears in the current release, SCOPe 2.08, called d2y3za1