Lineage for d1g2ua_ (1g2u A:)

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1005388Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 1005389Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 1005390Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits
  6. 1005391Protein 3-isopropylmalate dehydrogenase, IPMDH [53661] (9 species)
  7. 1005418Species Thermus thermophilus [TaxId:274] [53662] (14 PDB entries)
  8. 1005421Domain d1g2ua_: 1g2u A: [35036]
    mutant

Details for d1g2ua_

PDB Entry: 1g2u (more details), 2.1 Å

PDB Description: the structure of the mutant, a172v, of 3-isopropylmalate dehydrogenase from thermus thermophilus hb8 : its thermostability and structure.
PDB Compounds: (A:) 3-isopropylmalate dehydrogenase

SCOPe Domain Sequences for d1g2ua_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1g2ua_ c.77.1.1 (A:) 3-isopropylmalate dehydrogenase, IPMDH {Thermus thermophilus [TaxId: 274]}
mkvavlpgdgigpevteaalkvlraldeaeglglayevfpfggaaidafgepfpeptrkg
veeaeavllgsvggpkwdglprkirpetgllslrksqdlfanlrpakvfpglerlsplke
eiargvdvlivreltggiyfgeprgmseaeawnteryskpevervarvafevarkrrkhv
vsvdkanvlevgefwrktveevgrgypdvalehqyvdamamhlvrsparfdvvvtgnifg
dilsdlasvlpgslgllpsaslgrgtpvfepvhgsapdiagkgianptaailsaammleh
afglvelarkvedavakalletpppdlggsagteaftatvlrhla

SCOPe Domain Coordinates for d1g2ua_:

Click to download the PDB-style file with coordinates for d1g2ua_.
(The format of our PDB-style files is described here.)

Timeline for d1g2ua_: