SCOPe 2.02: Domain d2wkja_: 2wkj A:

Lineage for d2wkja_ (2wkj A:)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (13 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein automated matches [190095] (15 species)
   not a true protein

7. Species Escherichia coli [TaxId:562] [189174] (4 PDB entries)

8. Domain d2wkja_: 2wkj A: [169407]
   automated match to d1hl2a_
   complexed with 1pe, pyr; mutant

Details for d2wkja_

PDB Entry: 2wkj, 1.45 Å

PDB Description: crystal structure of the e192n mutant of e. coli n-acetylneuraminic acid lyase in complex with pyruvate at 1.45a resolution in space group p212121

PDB Compounds: (A:) n-acetylneuraminate lyase

SCOPe Domain Sequences for d2wkja_:

Sequence; same for both SEQRES and ATOM records:

>d2wkja_ c.1.10.1 (A:) automated matches {Escherichia coli [TaxId: 562]}
hhhatnlrgvmaalltpfdqqqaldkaslrrlvqfniqqgidglyvggstgeafvqslse
reqvleivaeeakgkikliahvgcvstaesqqlaasakrygfdavsavtpfyypfsfeeh
cdhyraiidsadglpmvvynipalsgvkltldqintlvtlpgvgalxqtsgdlyqmeqir
rehpdlvlyngydnifasgllagadggigstynimgwryqgivkalkegdiqtaqklqte
cnkvidlliktgvfrglktvlhymdvvsvplcrkpfgpvdekylpelkalaqqlmqer

Timeline for d2wkja_:

• d2wkja_ first appeared in SCOPe 2.01
  
• d2wkja_ appears in SCOPe 2.03
  
• d2wkja_ appears in the current release, SCOPe 2.08, called d2wkja1