SCOPe 2.08: Domain d2wipa1: 2wip A:1-298

Lineage for d2wipa1 (2wip A:1-298)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d2wipa1: 2wip A:1-298 [169376]
   Other proteins in same PDB: d2wipa2, d2wipb1, d2wipb2, d2wipc2, d2wipd1, d2wipd2
   automated match to d1vywa_
   complexed with p49, so4

Details for d2wipa1

PDB Entry: 2wip, 2.8 Å

PDB Description: structure of cdk2-cyclin a complexed with 8-anilino-1-methyl-4,5- dihydro- 1h-pyrazolo[4,3-h] quinazoline-3-carboxylic acid

PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wipa1:

Sequence, based on SEQRES records:

>d2wipa1 d.144.1.7 (A:1-298) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records):

>d2wipa1 d.144.1.7 (A:1-298) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigvvykarnkltgevvalkkirldtetegvpstaireisllkelnhpnivk
lldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
rdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavd
iwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwar
qdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2wipa1:

• d2wipa1 first appeared in SCOPe 2.01, called d2wipa_
  
• d2wipa1 appears in SCOPe 2.07