SCOPe 2.08: Domain d2wipc1: 2wip C:1-296

Lineage for d2wipc1 (2wip C:1-296)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d2wipc1: 2wip C:1-296 [169377]
   Other proteins in same PDB: d2wipa2, d2wipb1, d2wipb2, d2wipc2, d2wipd1, d2wipd2
   automated match to d1vywa_
   complexed with p49, so4

Details for d2wipc1

PDB Entry: 2wip, 2.8 Å

PDB Description: structure of cdk2-cyclin a complexed with 8-anilino-1-methyl-4,5- dihydro- 1h-pyrazolo[4,3-h] quinazoline-3-carboxylic acid

PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wipc1:

Sequence, based on SEQRES records:

>d2wipc1 d.144.1.7 (C:1-296) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Sequence, based on observed residues (ATOM records):

>d2wipc1 d.144.1.7 (C:1-296) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigvvykarnkltgevvalkkirldtetegvpstaireisllkelnhpnivk
lldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
rdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavd
iwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwar
qdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d2wipc1:

• d2wipc1 first appeared in SCOPe 2.01, called d2wipc_
  
• d2wipc1 appears in SCOPe 2.07