SCOPe 2.08: Domain d2gigb_: 2gig B:

Lineage for d2gigb_ (2gig B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.19: Restriction endonuclease HincII [69525] (1 protein)
   automatically mapped to Pfam PF09226

6. Protein Restriction endonuclease HincII [69526] (1 species)

7. Species Haemophilus influenzae [TaxId:727] [69527] (19 PDB entries)
   Uniprot P17743 ! Uniprot P44413

8. Domain d2gigb_: 2gig B: [164713]
   automated match to d1kc6a_
   protein/DNA complex; complexed with na

Details for d2gigb_

PDB Entry: 2gig, 1.83 Å

PDB Description: alteration of sequence specificity of the type ii restriction endonuclease hincii through an indirect readout mechanism

PDB Compounds: (B:) Type II restriction enzyme HincII

SCOPe Domain Sequences for d2gigb_:

Sequence, based on SEQRES records:

>d2gigb_ c.52.1.19 (B:) Restriction endonuclease HincII {Haemophilus influenzae [TaxId: 727]}
sfikpiyqdinsiligqkvkrpksgtlsghaagepfeklvykflkenlsdltfkqyeyln
dlfmknpaiighearyklfnsptllfllsrgkaatenwsienlfeekqndtadillvkdq
fyelldvktrnisksafapniisayklaqtcakmidnkefdlfdinylevdwelngedlv
cvstsfaelfksepselyinwaaamqiqfhvrdldqgfngtreewaksylkhfvtqaeqr
aismidkfvkpfkkyi

Sequence, based on observed residues (ATOM records):

>d2gigb_ c.52.1.19 (B:) Restriction endonuclease HincII {Haemophilus influenzae [TaxId: 727]}
sfikpiyqdinsiligqkvfeklvykflkenlsdltfkqyeylndlfmknpaiigheary
klfnsptllfllsrgkaatenwsienlfeekqndtadillvkdqfyelldvktrnisksa
fapniisayklaqtcakmidnkefdlfdinylevdwelngedlvcvstsfaelfksepse
lyinwaaamqiqfhvrdldqgfngtreewaksylkhfvtqaeqraismidkfvkpfkkyi

Timeline for d2gigb_:

• d2gigb_ first appeared in SCOPe 2.01
  
• d2gigb_ appears in SCOPe 2.07