SCOPe 2.01: Domain d3chsa2: 3chs A:1-208

Lineage for d3chsa2 (3chs A:1-208)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.98: Leukotriene A4 hydrolase N-terminal domain [63736] (1 superfamily)
   duplication: two beta-sandwiches of similar topologies are fused together in a single three beta-sheet domain

4. Superfamily b.98.1: Leukotriene A4 hydrolase N-terminal domain [63737] (1 family)

5. Family b.98.1.1: Leukotriene A4 hydrolase N-terminal domain [63738] (1 protein)

6. Protein Leukotriene A4 hydrolase N-terminal domain [63739] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63740] (15 PDB entries)
   Uniprot P09960

8. Domain d3chsa2: 3chs A:1-208 [156654]
   Other proteins in same PDB: d3chsa1, d3chsa3
   automatically matched to d1gw6a2
   complexed with 4bu, imd, yb, zn

Details for d3chsa2

PDB Entry: 3chs, 2.55 Å

PDB Description: crystal structure of leukotriene a4 hydrolase in complex with (2s)-2- amino-5-[[4-[(2s)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo- pentanoic acid

PDB Compounds: (A:) Leukotriene A-4 hydrolase

SCOPe Domain Sequences for d3chsa2:

Sequence; same for both SEQRES and ATOM records:

>d3chsa2 b.98.1.1 (A:1-208) Leukotriene A4 hydrolase N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
peivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdlt
iekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltp
eqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpd
pedpsrkiykfiqkvpipcylialvvga

Timeline for d3chsa2:

• d3chsa2 first appeared in SCOP 1.75
  
• d3chsa2 appears in SCOPe 2.02
  
• d3chsa2 appears in the current release, SCOPe 2.08